The meaning of the name Oprah is Gazelle. The origin of the name Oprah is Hebrew. This is the culture in which the name originated, or in the case of a word, the language.
Oprah is a created name, made famous by Oprah Winfrey, talk show host. Winfrey says that her name was originally Orpah on her birth certificate, but was constantly being mispronounced by her family. They legally changed her name to Oprah at the age of 1.