The name Isaac is of Hebrew origin and means "He Will Laugh." The origin is the culture in which the name originated, or in the case of a word--the language in which it most appears.
Variations of the name Isaac include Itzhak, Issac, Isaak, and Isaack. Comman nicknames for the name Isaac are Is and Izzy. Sir Isaac Newton (physicist and mathematician) is one of the most famous Isaacs. Other famous Isaacs include sci-fi author Isaac Asimov, athletes Isaac Bruce, Isaak Davis, and Isaac Hamilton. Isaac Hayes is a singer and Isaac Mizrahi is a popular fashion designer. Isaac Bashevis Singer won the Novel prize for literature in 1978. Fictional characters with the name Isaac include the main character in Woody Allen’s Manhattan. Isaac Jaffe from the television show Sports Night and Isaac Mendez from the show Heroes.